Pesticide Effect in Male Hormones and Antioxidant Status in Male Albino Rats

Reproductive health problem is more common nowadays and various causes like nutritional defect, socio-economic problems, life style changes are reason for that, among those reason, one important factor is environmental factor. In this study, the pesticide, Lindane is used to induce reproductive toxicity and the levels of male reproductive hormone, antioxidant and histopathology of rat testis was evaluated. Ten healthy rats were treated with Lindane (5 mg/kg) for 30 d. Lindane treated rats showed decreased male hormone and antioxidant levels when compared to control. Histopathology of rat testis showed cleavage of seminiferous tubules, with detached germ cells from the basement membrane and the intracellular space between seminiferous tubule is abnormal. Result implies Lindane reproductive toxicity.